Pseudomonas mendocina Meningitis in a Postoperative Patient: A Case Report and Review of Literature
Published: May 1, 2023 | DOI: https://doi.org/10.7860/JCDR/2023/61792.17859
Mitra Kar, Akanksha Dubey, Chinmoy Sahu, Sangram Singh Patel
1. Senior Resident, Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
2. Senior Resident, Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
3. Additional Professor, Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
4. Associate Professor, Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Correspondence
Dr. Chinmoy Sahu,
Additional Professor, Department of Microbiology, Sanjay Gandhi Institute of Medical Sciences, Lucknow-226014, Uttar Pradesh, India.
E-mail: csahu78@rediffmail.com
Pseudomonas mendocina is a Gram negative bacillus belonging to the Pseudomonadaceae family. It was first isolated in 1970 from soil and water in the Mendoza region of Argentina. Although it rarely causes infection, 21 cases of infections ranging from infective endocarditis, bacteraemia, meningitis, soft tissue infections, and urinary tract infections have been reported worldwide, mostly among patients with underlying co-morbidities. This report is the first case of pyogenic meningitis due to Pseudomonas mendocina reported from a 1600-bed teaching hospital in Northern India and the second case of Pseudomonas mendocina infection from the Indian subcontinent. The presented case was of a 31-year-old female who was diagnosed with pituitary macroadenoma on Magnetic Resonance Imaging (MRI). She underwent endoscopic endonasal trans-sphenoidal excision of the tumour after two months of diagnosing the tumour, following which she developed meningitis. On two consecutive aerobic bacterial cultures and identification by Matrix-Assisted Laser Desorption/Ionisation-Time of Flight-Mass Spectrometry (MALDI-TOF-MS), growth of Pseudomonas mendocina was observed. After Antibiotic Sensitivity Testing (AST), the patient was started on Piperacillin-tazobactam and Amoxicillin-clavulanic acid which alleviated her symptoms of meningitis and she was discharged after 27 days of hospital stay.
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