Papillary Carcinoma of Thyroglossal Cyst in a Background of Hashimoto’s Thyroiditis: A Case Report
Published: July 1, 2024 | DOI: https://doi.org/10.7860/JCDR/2024/70516.19595
Glory Deoja, Renu Gboy Varghese, Kevin Manuel, Peter Manoharan
1. Postgraduate Student, Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry, India.
2. Professor, Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry, India.
3. Associate Professor, Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry, India.
4. Professor, Department of General Surgery, Pondicherry Institute of Medical Sciences, Puducherry, India.
Correspondence Address :
Dr. Glory Deoja,
Postgraduate Student, Department of Pathology, Pondicherry Institute of Medical Sciences, Kalapet, Puducherry-605014, India.
E-mail: glorydeoja@gmail.com
Abstract
Thyroglossal Duct Cyst (TGDC) is one of the most common congenital neck anomalies that occur due to incomplete involution of the thyroglossal duct. Carcinoma arising in TGDC is rare, accounting for about 1% of cases, with non neoplastic thyroid gland lesions even rarer. This report demonstrates a case of papillary carcinoma with Hashimoto Thyroiditis (HT) of TGDC in the background of HT in the thyroid gland. A 51-year-old woman presented with complaints of midline neck swelling for the past 20 years. Ultrasound revealed an infected thyroglossal cyst. Fine Needle Aspiration Cytology (FNAC) was inconclusive, and the cystic lesion was excised and sent for histopathology. Histopathology showed a thyroglossal cyst with papillary carcinoma along with a focus of HT. The patient underwent total thyroidectomy after a month, which showed features of HT and nodular hyperplasia. There was no evidence of papillary carcinoma in the thyroidectomy specimen. TGDC can harbour malignancies accounting for about 1% of cases. Since TGDC has ectopic thyroid tissue, they should be evaluated for neoplastic and non neoplastic lesions. Also, the evaluation of the thyroid gland is essential for identifying the presence of malignancy to confirm a primary or secondary metastatic carcinoma in a TGDC.
Keywords
Midline neck swelling, Sistrunk procedure, Thyroid, Thyroid carcinoma